SELECTED PUBLICATIONS

Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. 2010. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proc Natl Acad Sci U S A. 107(11):5012-7.

Lake RJ, Grimm LM, Veraksa A, Banos A, Artavanis-Tsakonas S. 2009. In vivo analysis of the Notch receptor S1 cleavage. PLoS One 4(8):e6728.

Fre S, Pallavi SK, Huyghe M, LaƩ M, Janssen KP, Robine S, Artavanis-Tsakonas S, Louvard D. 2009. Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine. Proc Natl Acad Sci U S A. 106(15):6309-14.

Hurlbut GD, Kankel MW, Artavanis-Tsakonas S. 2009. Nodal points and complexity of Notch-Ras signal integration. Proc Natl Acad Sci U S A. 106(7):2218-23.

Chang HC, Dimlich DN, Yokokura T, Mukherjee A, Kankel MW, Sen A, Sridhar V, Fulga TA, Hart AC, Van Vactor D, Artavanis-Tsakonas S. 2008. Modeling spinal muscular atrophy in Drosophila. PLoS One 3(9):e3209.

Arboleda-Velasquez JF, Zhou Z, Shin HK, Louvi A, Kim HH, Savitz SI, Liao JK, Salomone S, Ayata C, Moskowitz MA, Artavanis-Tsakonas S. 2008. Linking Notch signaling to ischemic stroke. Proc Natl Acad Sci U S A. 105(12):4856-61.

Kankel MW, Hurlbut GD, Upadhyay G, Yajnik V, Yedvobnick B, Artavanis-Tsakonas, S. 2007. Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector. Genetics 177:2493-505.

Kelly, D.F., Lake, R.J., Walz, T., Artavanis-Tsakonas, S. 2007. Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless. Proc Natl Acad Sci U S A. 23:9591-6.

Hurlbut, G.D., Kankel, M.W., Lake, R.J., Artavanis-Tsakonas, S. 2007. Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol. 19(2):166-175.

Klinakis, A., Szabolcs, M., Politi, K., Kiaris, H., Artavanis-Tsakonas, S., Efstratiadis, A. 2006. Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice. Proc Natl Acad Sci U S A. 19(2):166-175.

Louvi, A., Arboleda-Velasquez, J., Artavanis-Tsakonas, S. 2006. CADASIL: a critical look at a Notch disease. Dev Neurosci. (28): 5-12.

Mourikis, P., Hurlbut, G.D., and Artavanis-Tsakonas, S. 2006. Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. Proc Natl Acad Sci U S A. (5):1307-12.

Louvi, A., and Artavanis-Tsakonas, S. 2006. Notch signalling in neural development. Nature Rev Neurosci. (2): 93-102. Nature Rev Neurosci. (2): 93-102.

Mukherjee, A., Veraksa, A., Bauer, A., Rosse, C., Camonis, J., and Artavanis-Tsakonas, S.. 2005. Regulation of Notch signalling by non-visual beta-arrestin. Nature Cell Biol. (12): 1191-201.

Fre, S., Huyghe, M., Mourikis, P., Robine, S., Louvard, D., and Artavanis-Tsakonas S. 2005. Notch signals control the fate of immature progenitor cells in the intestine. Nature 435: 964-968.

Veraksa, A., Bauer, A., and Artavanis-Tsakonas, S.. 2005. Analyzing protein complexes in Drosophila with Tandem Affinity Purification-mass spectrometry. Dev. Dyn. 232: 827-834.

Moberg, K.H., Mukherjee, A., Veraksa, A., Artavanis-Tsakonas, S.., Hariharan, I.K. 2004. The Drosophila F Box Protein Archipelago Regulates dMyc Protein Levels In Vivo. Curr. Biol. 14: 965-974.

Artavanis-Tsakonas S. 2004. Accessing the Exelixis collection. Nat Genet. 36: 207

Beltran, S., Blanco, E., Serras, F., Perez-Villamil, B., Guigo, R., Artavanis-Tsakonas S., Corominas, M. 2003. Transcriptional network controlled by the trithorax-group gene ash2 in Drosophila melonogaster. Proc Natl Acad Sci U S A 100: 196-200.

Grandbarbe, L., Bouissac, J., Rand, M., Hrabe de Angelis, M., Artavanis-Tsakonas S., Mohier, E. 2003. Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development 130: 1391-1402.

Mishra-Gorur, K., Rand, M.D., Perez-Villamil, B., Artavanis-Tsakonas S. 2002. Down-regulation of Delta by proteolytic processing. J Cell Biol 159: 313.324.

Matsuno K., Ito M., Hori K., Miyashita F., Suzuki S., Kishi N., Artavanis-Tsakonas S., Okano H. 2002. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development 129: 1049-1059.

Kiaris H., Schally A.V., Busto R., Halmos G., Artavanis-Tsakonas S., Varga J.L. 2002. Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs. Proc Natl Acad Sci U S A 99: 3293-3298.

Kishi N., Tang Z., Maeda Y., Hirai A., Mo R., Ito M., Suzuki S., Nakao K., Kinoshita T., Kadesch T., Hui C., Artavanis-Tsakonas S., Okano H., Matsuno K. 2001. Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis. Int. J. Dev. Neurosci. 19: 21-35.

Wu, L., Aster, J.C., Blacklow, S.C., Lake, R., Artavanis-Tsakonas, S., Griffin, J.D. 2000. MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors. Nat Genet. 26: 484-489.

Rand, M.D., Grimm, L.M., Artavanis-Tsakonas, S., Patriub, V., Blacklow, S.C., Sklar, J., and Aster, J.C. 2000. Calcium depletion dissociates and activates heterodimeric notch receptors. Mol. Cell Biol. 20: 71825-1835.

Hing, H.K., Bangalore, L., Sun, X., and Artavanis-Tsakonas, S. 1999. Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling. Eur. J. Cell Biol. 78: 690-697.

Sestan, N., Artavanis-Tsakonas, S., and Rakic, P. 1999. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 286: 741-746.

Purcell, K., and Artavanis-Tsakonas, S.. 1999. The developmental role of warthog, the notch modifier encoding Drab6. J. Cell Biol. 136: 731-740.

Cornell, M., Evans, D.A., Mann, R., Fostier, M., Flasza, M., Monthatong, M., Artavanis-Tsakonas, S., Baron, M. 1999. The drosophila melanogaster suppressor of deltex gene, a regulator of the notch receptor signaling pathway, is an E3 class ubiquitin ligase. Genetics 152: 567-576.

Artavanis-Tsakonas, S., Rand, M.D., and Lake, R.J. 1999. Notch signaling: cell fate control and signal integration in development. Science 284: 770-776.

Gray, G.E., Mann, R.S., Mitsiadis, E., Henrique, D., Carcangiu, M,L., Banks, A., Leiman, J., Ward, D., Ish-Horowitz, D., and Artavanis-Tsakonas, S. 1999. Human ligands of the notch receptor. Am. J. Pathol. 154: 785-794.

Qi, H., Rand, M.D., Wu, X., Sestan, N., Wang, W., Rakic, P., Xu, T., and Artavanis-Tsakonas, S. 1999. Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian. Science 283: 91-94.

[more references]